The role of parathyroid hormone (pth) in the 6-month prognosis of patients with chronic heart failure hospitalized in the cardiac unit of university hospitals of ahvaz city in 2015-2016

Seyed Mohammad Hassan Adel, Sarvenaz Soltani, Zhiva Taherpour

Abstract


Background and aim:Chronic heart failure (CHF) syndrome is the most common cause of hospitalization in patients over 65 years of age. HF is a clinical disorder that occurs due to impairment in the structure or function of the heart as inherent or acquired, and causes clinical symptoms. Therefore, the purpose of this study was to evaluate the role of parathyroid hormone (PTH) in the 6-month prognosis of patients with chronic heart failure hospitalized in the cardiac unit of university hospitals of Ahvaz city in 2015-2016. Materials and methods: This study is a descriptive epidemiologic study. In this study, a total of 202 people were enrolled in the study, of which 126 (62.3%) were male and 76 (37.6%) were female, and patients classified for HF according to Framingham criteria and in the subgroup of systolic HF (with an ejection fraction of less than or equal to 40%) and hospitalized in the heart unit of Imam Khomeini Hospital in Ahvaz during the year 2015-2016 were enrolled in the study. Findings: The results showed that the chance of stroke and death in people with a PTH of more than 39 pg/ml is 5.85 times more than those with PTH of less than 39 pg/ml, and with the rise in the NYHA, PTH has also increased.Discussion and Conclusion: According to the evaluations conducted in this study, it was found that PTH is related to the severity of heart failure and subsequently its short-term prognosis. Therefore, it seems that during the first hospitalization of patients with heart failure, measurement of PTH can play a significant role in clarifying patients' clinical condition and predicting their short-term prognosis, and subsequently changing of the therapeutic route.

Keywords


Heart failure, NYHA class, PTH

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