Pleural involvement and dyspnea as primary presentations of an occult gastric cancer: a case report

Fereshteh Vosough, Behnood Farazmand

Abstract


Herein, we reported a case of malignant pleural effusion as the initial metastatic presentation of occult gastric cancer in a 52-year-old diabetic woman. This is the first report of gastric cancer metastasized to pleura as a primary presentation. The pathologic results of adenocarcinoma pleural specimens were indicative of an undifferentiated cancer. Based on the results of immunohistochemistry, we suggested the metastasis of gastric cancer. For patients with such distinct clinical presentations, it would be suitable to study gastric cancer as one of the probable primary sites.


Keywords


Gastric Cancer, Occult Gastric Cancer, Pleura, Case report

Full Text:

PDF

References


Sano T, Coit DG, Kim HH, Roviello F, Kassab P, Wittekind C, et al. Proposal of a new stage grouping of gastric cancer for TNM classification: International Gastric Cancer Association staging project. Gastric cancer. 2017;20(2):217-25.

Hato S, Iwasaki Y, Mizusawa J, Terashima M, Katai H, Yoshikawa T, et al. Effectiveness and limitations of staging laparoscopy for peritoneal metastases in advanced gastric cancer from the results of JCOG0501: A randomized trial of gastrectomy with or without neoadjuvant chemotherapy for type 4 or large type 3 gastric cancer. American Society of Clinical Oncology; 2017.

Mehta DP, Bohra M, Anand AS, Parikh S, Shah SA. Rare presenting features of carcinoma of stomach–Leptomeningeal carcinomatosis, breast metastasis, malignant pleural effusion, and dermatoses: A report of two cases and review of literature. Medical Journal of Dr DY Patil Vidyapeeth. 2017;10(6):576.

Mahajan AK, Collins DT, Powers C, Khandhar SJ. Tunneled pleural catheters for management of malignant pleural effusions: a 2-year review of outcomes at a high-volume center. Shanghai Chest. 2018;2(4).

Riihimaki M, Hemminki A, Sundquist K, Sundquist J, Hemminki K. Metastatic spread in patients with gastric cancer. Oncotarget. 2016 Aug 9;7(32):52307-16. PubMed PMID: 27447571. Pubmed Central PMCID: PMC5239553. Epub 2016/07/23. eng.

Yoon SY, Kim JH, Kim WS, Chung HW, Lee MH, Kim SY, et al. Pleural Metastasis as Initial Presentation of Occult Gastric Cardia Cancer: A Possible Role of PET-CT in Diagnosis. Cancer research and treatment: official journal of Korean Cancer Association. 2014;46(4):415.

Maeda H, Okabayashi T, Nishimori I, Sugimoto T, Namikawa T, Dabanaka K, et al. Clinicopathologic features of adenocarcinoma at the gastric cardia: is it different from distal cancer of the stomach? Journal of the American College of Surgeons. 2008;206(2):306-10.

Kim JY, Lee HS, Kim N, Shin CM, Lee SH, Park YS, et al. Prevalence and clinicopathologic characteristics of gastric cardia cancer in South Korea. Helicobacter. 2012;17(5):358-68.

Xie SL, Yang MH, Chen K, Huang H, Zhao XW, Zang YS, et al. Efficacy of Arsenic Trioxide in the Treatment of Malignant Pleural Effusion Caused by Pleural Metastasis of Lung Cancer. Cell biochemistry and biophysics. 2015 Apr;71(3):1325-33. PubMed PMID: 25413961. Epub 2014/11/22. eng.

Jiang S, Wang G, Dong Y. Endostar combined with chemotherapy in a pediatric osteosarcoma with pulmonary metastasis and malignant pleural effusion: A case report. Medicine. 2017;96(51):e9077.


Refbacks

  • There are currently no refbacks.




Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Revista Publicando.

Licencia de Creative Commons

 

This Content is available under licencia de Creative Commons Reconocimiento-NoComercial-CompartirIgual 4.0 Internacional.